Taxewell-RTU


Docetaxel Injection (Ready to Use)

Prescribing Information :

Docetaxel-Injection-Taxe-RTU-20mg

Strength:

20mg/ml

Description:

Single Dose Vial, One Vial Formulation. Ready to add to infusion solution.

Pack Size:

1 vial

Storage Conditions:

Store at a temperature not exceeding 25°C (77°F). Protect from light.

Docetaxel-Injection-Taxe-RTU-80mg

Strength:

80mg/4ml

Description:

Single Dose Vial, One Vial Formulation. Ready to add to infusion solution.

Pack Size:

1 vial

Storage Conditions:

Store at a temperature not exceeding 25°C (77°F). Protect from light.

Docetaxel-Injection-Taxe-RTU-120mg

Strength:

120mg/6ml

Description:

Single Dose Vial, One Vial Formulation. Ready to add to infusion solution.

Pack Size:

1 vial

Storage Conditions:

Store at a temperature not exceeding 25°C (77°F). Protect from light.

Approved Indications of Taxewell-RTU



  • NSCLC

  • Metastatic Breast Cancer

  • Hormone Refractory Prostate Cancer (HRPC)

  • Gastric Adenocarcinoma (GC)

  • Squamous Cell Carcinoma of the Head and Neck Cancer (SCCHN)





Product Information



Getwell Pharmaceuticals is a leading manufacturer and supplier of Docetaxel Injection- Taxewell RTU at a cost effective price in India. We have a range of complex generics and drug delivery based formulations.



Dosage of Docetaxel injection



Docetaxel is strictly recommended to be used as I.V. infusion only.



Recommended Dose:



Breast Cancer: The recommended dose of Docetaxel is 60-100 mg/m administered intravenously over 1 hour every 3 weeks



Non Small Cell Lung Cancer (NSCLC): The recommended dose is 75 mg/m administered intravenously over 1 hour every 3 2 weeks



Prostate cancer: For hormone refractory metastatic prostate cancer, the recommended dose of Docetaxel is 75 2 mg/m every 3 weeks as a 1 hour intravenous infusion along with continuous administration of prednisone 5 mg (oral) twice daily.



Gastric adenocarcinoma: For gastric adenocarcinoma, the recommended dose of Docetaxel is 75 mg/m as 1 hour 2 intravenous infusion, followed by cisplatin 75 mg/m, as 1 to 3 hour intravenous infusion (both on 2 day 1 only), followed by fluorouracil 750 mg/m per day given as 24 hour continuous intravenous infusion for 5 days, starting at the end of the cisplatin infusion.



Treatment is repeated every three weeks. Patients must receive premedication with antiemetic and appropriate hydration for cisplatin administration



Side effects of Docetaxel injection



The most serious adverse reactions from Docetaxel Injection are:




  • Toxic Deaths

  • Hepatotoxicity

  • Neutropenia

  • Hypersensitivity

  • Fluid Retention

  • Acute Myeloid Leukaemia

  • Neurologic Reaction

  • Asthenia



Contraindications of Docetaxel injection



Docetaxel is contraindicated in patients who have a history of severe hypersensitivity reactions to docetaxel or to other drugs formulated with polysorbate 80. Severe reactions including anaphylaxis, have occurred. Docetaxel should not be used in patients with neutrophil counts of <1500cells/mm, Pregnant women, During Breast Feeding, Patients with severe liver impairment.


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